在生物医学自然语言处理中，命名实体识别（NER）和命名实体归一化（NEN）是能够从不断增长的生物医学文献中自动提取生物医学实体（例如，疾病和化学品）的关键任务。在本文中，我们展示了伯尔尼（高级生物医学实体识别和归一化），这是一种改善以前的基于神经网络的NER工具的工具（Kim等，2019），采用多任务NER模型和基于神经网络的NEN模型实现更快，更准确的推理。我们希望我们的工具可以帮助为各种任务等诸如生物医学知识图形建设等各种任务来诠释大规模生物医学文本。

执行命名实体识别（ner）时，实体长度是可变的，并且依赖于特定域或数据集。预先训练的语言模型（PLM）用于解决NER任务，并且倾向于偏向于数据集模式，例如长度统计，表面形式和偏斜类分布。这些偏差阻碍了PLMS的泛化能力，这对于在现实世界情况下解决许多看不见的提及是必要的。我们提出了一种新型的脱叠方法雷鬼，以改善不同长度的实体的预测。要缩小评估与实际情况之间的差距，我们在包含看不见组的分区基准数据集上评估了PLMS。在这里，Regler对长期目的进行了重大改进，可以通过在实体内的结合或特殊字符上进行扩展来预测。此外，大多数ner数据集中存在严重的类别不平衡，导致易消极的例子在训练期间支配，例如“”。我们的方法通过降低易消极的例子的影响来减轻偏斜阶级分布。关于生物医学和一般域的广泛实验证明了我们方法的泛化能力。为了促进可重复性和未来的工作，我们发布了我们的代码。“https://github.com/minstar/regler”

Crowdsourcing has emerged as an effective platform to label a large volume of data in a cost- and time-efficient manner. Most previous works have focused on designing an efficient algorithm to recover only the ground-truth labels of the data. In this paper, we consider multi-choice crowdsourced labeling with the goal of recovering not only the ground truth but also the most confusing answer and the confusion probability. The most confusing answer provides useful information about the task by revealing the most plausible answer other than the ground truth and how plausible it is. To theoretically analyze such scenarios, we propose a model where there are top-two plausible answers for each task, distinguished from the rest of choices. Task difficulty is quantified by the confusion probability between the top two, and worker reliability is quantified by the probability of giving an answer among the top two. Under this model, we propose a two-stage inference algorithm to infer the top-two answers as well as the confusion probability. We show that our algorithm achieves the minimax optimal convergence rate. We conduct both synthetic and real-data experiments and demonstrate that our algorithm outperforms other recent algorithms. We also show the applicability of our algorithms in inferring the difficulty of tasks and training neural networks with the soft labels composed of the top-two most plausible classes.

Nowadays, fake news easily propagates through online social networks and becomes a grand threat to individuals and society. Assessing the authenticity of news is challenging due to its elaborately fabricated contents, making it difficult to obtain large-scale annotations for fake news data. Due to such data scarcity issues, detecting fake news tends to fail and overfit in the supervised setting. Recently, graph neural networks (GNNs) have been adopted to leverage the richer relational information among both labeled and unlabeled instances. Despite their promising results, they are inherently focused on pairwise relations between news, which can limit the expressive power for capturing fake news that spreads in a group-level. For example, detecting fake news can be more effective when we better understand relations between news pieces shared among susceptible users. To address those issues, we propose to leverage a hypergraph to represent group-wise interaction among news, while focusing on important news relations with its dual-level attention mechanism. Experiments based on two benchmark datasets show that our approach yields remarkable performance and maintains the high performance even with a small subset of labeled news data.

Any classifier can be "smoothed out" under Gaussian noise to build a new classifier that is provably robust to $\ell_2$-adversarial perturbations, viz., by averaging its predictions over the noise via randomized smoothing. Under the smoothed classifiers, the fundamental trade-off between accuracy and (adversarial) robustness has been well evidenced in the literature: i.e., increasing the robustness of a classifier for an input can be at the expense of decreased accuracy for some other inputs. In this paper, we propose a simple training method leveraging this trade-off to obtain robust smoothed classifiers, in particular, through a sample-wise control of robustness over the training samples. We make this control feasible by using "accuracy under Gaussian noise" as an easy-to-compute proxy of adversarial robustness for an input. Specifically, we differentiate the training objective depending on this proxy to filter out samples that are unlikely to benefit from the worst-case (adversarial) objective. Our experiments show that the proposed method, despite its simplicity, consistently exhibits improved certified robustness upon state-of-the-art training methods. Somewhat surprisingly, we find these improvements persist even for other notions of robustness, e.g., to various types of common corruptions.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Proximal Policy Optimization (PPO) is a highly popular policy-based deep reinforcement learning (DRL) approach. However, we observe that the homogeneous exploration process in PPO could cause an unexpected stability issue in the training phase. To address this issue, we propose PPO-UE, a PPO variant equipped with self-adaptive uncertainty-aware explorations (UEs) based on a ratio uncertainty level. The proposed PPO-UE is designed to improve convergence speed and performance with an optimized ratio uncertainty level. Through extensive sensitivity analysis by varying the ratio uncertainty level, our proposed PPO-UE considerably outperforms the baseline PPO in Roboschool continuous control tasks.

Diffusion-based generative models have achieved remarkable success in image generation. Their guidance formulation allows an external model to plug-and-play control the generation process for various tasks without fine-tuning the diffusion model. However, the direct use of publicly available off-the-shelf models for guidance fails due to their poor performance on noisy inputs. For that, the existing practice is to fine-tune the guidance models with labeled data corrupted with noises. In this paper, we argue that this practice has limitations in two aspects: (1) performing on inputs with extremely various noises is too hard for a single model; (2) collecting labeled datasets hinders scaling up for various tasks. To tackle the limitations, we propose a novel strategy that leverages multiple experts where each expert is specialized in a particular noise range and guides the reverse process at its corresponding timesteps. However, as it is infeasible to manage multiple networks and utilize labeled data, we present a practical guidance framework termed Practical Plug-And-Play (PPAP), which leverages parameter-efficient fine-tuning and data-free knowledge transfer. We exhaustively conduct ImageNet class conditional generation experiments to show that our method can successfully guide diffusion with small trainable parameters and no labeled data. Finally, we show that image classifiers, depth estimators, and semantic segmentation models can guide publicly available GLIDE through our framework in a plug-and-play manner.

This work introduces alternating latent topologies (ALTO) for high-fidelity reconstruction of implicit 3D surfaces from noisy point clouds. Previous work identifies that the spatial arrangement of latent encodings is important to recover detail. One school of thought is to encode a latent vector for each point (point latents). Another school of thought is to project point latents into a grid (grid latents) which could be a voxel grid or triplane grid. Each school of thought has tradeoffs. Grid latents are coarse and lose high-frequency detail. In contrast, point latents preserve detail. However, point latents are more difficult to decode into a surface, and quality and runtime suffer. In this paper, we propose ALTO to sequentially alternate between geometric representations, before converging to an easy-to-decode latent. We find that this preserves spatial expressiveness and makes decoding lightweight. We validate ALTO on implicit 3D recovery and observe not only a performance improvement over the state-of-the-art, but a runtime improvement of 3-10$\times$. Project website at https://visual.ee.ucla.edu/alto.htm/.

Recent studies have proposed a unified user modeling framework that leverages user behavior data from various applications. Most benefit from utilizing users' behavior sequences as plain texts, representing rich information in any domain or system without losing generality. Hence, a question arises: Can language modeling for user history corpus help improve recommender systems? While its versatile usability has been widely investigated in many domains, its applications to recommender systems still remain underexplored. We show that language modeling applied directly to task-specific user histories achieves excellent results on diverse recommendation tasks. Also, leveraging additional task-agnostic user histories delivers significant performance benefits. We further demonstrate that our approach can provide promising transfer learning capabilities for a broad spectrum of real-world recommender systems, even on unseen domains and services.